Scientists have developed the first fast, low-cost DNA test to allow doctors to diagnose inherited diseases such as cystic fibrosis.

The technique, which is to be used by researchers and medics only, would use a drop of saliva to reveal variations in a person’s genetic code at critical points along the DNA chain.

Tiny differences or omissions in DNA code can determine whether or not a person is healthy, susceptible to disease, or has a serious or life-threatening condition.

Juan Diaz-Mochon of the University of Edinburgh’s School of Chemistry, who led the research, said they could test for cystic fibrosis (CS), age-related macular disease and some genetic mutations. At present, CS can be difficult and lengthy to diagnose.

The technology, which was funded by Scottish Enterprise, should be ready for widespread use within months. It will at first be used by research centres, then in its second phase will go out to the NHS.

Dr Diaz-Mochon said it was a simpler and much more robust way of testing than at present. It only took half-an-hour and the method, based on chemical analysis, delivered reliable results without the need for expensive enzymes used in conventional DNA testing.

“This technology offers a speedy, cost-efficient alternative to existing methods of DNA analysis. The market for DNA testing is quickly expanding as it becomes more affordable. Our method could help reach the goal of complete genome analysis in a few hours,” he added.

Professor Mark Bradley of the University’s School of Chemistry, who also took part in the study, said: “We plan to test the technology further, extend our collaborations with leading researchers and companies in the DNA sequencing field and establish our first commercial operations within the next six months.”

DNAWellnessinfo.com Resource:  http://www.timesonline.co.uk/tol/news/uk/scotland/article7028327.ece